This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
Aliases： EKLF; INLU; HBFQTL6
Entrez GeneID： 10661
Swissprot ： Q13351
WB Predicted band size： 38.2kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. Coli.
