This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
Aliases： JMJD2; JHDM3A; JMJD2A; TDRD14A
Entrez GeneID： 9682
Swissprot： O75164
WB Predicted band size ： 120.6kDa
Host/Isotype ： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human KDM4A (AA: 932-1057) expressed in E. Coli.
