This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Aliases： DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
Entrez GeneID： 3728
Swissprot ： P14923
WB Predicted band size： 82kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human JUP expressed in E. Coli.
