This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Aliases ： JTK10; JAK2
Entrez GeneID： 3717
Swissprot ： O60674
WB Predicted band size ： 130.6kDa
Host/Isotype： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.
