The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
Aliases： KOC; CT98; IMP3; KOC1; IMP-3; VICKZ3
Entrez GeneID： 10643
Swissprot： O00425
WB Predicted band size： 63.7kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human IGF2BP3 (AA: 430-579) expressed in E. Coli.
