Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
Aliases : H3; H3.2; H3/M; H3F2; H3FM; H3FN
Entrez GeneID: 126961
Swissprot: Q71DI3
WB Predicted band size: 15.4kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen : Synthesized peptide of human HIST2H3C (AA: ATKAARK(Ac)SAPATGGV).
