This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]
Aliases: HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73
Entrez GeneID: 2034
Swissprot: Q99814
WB Predicted band size : 96.5kDa
Host/Isotype : Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human HIF2a (AA: 680-870) expressed in E. Coli.
