This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases： KA1; EAA1; GRIK; GluK4
Entrez GeneID： 2900
Swissprot ： Q16099
WB Predicted band size： 107.2kDa
Host/Isotype： Mouse IgG2b
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human GRIK4 (AA: extra 21-166) expressed in E. Coli.
