GABPA: GA binding protein transcription factor, alpha subunit 60kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.
Aliases： NFT2; NRF2
Entrez GeneID： 2551
Swissprot： Q06546
WB Predicted band size： 51kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human,Mouse
Immunogen ： Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.
