Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]
Aliases : HPS; HFREP1; HP-041; LFIRE1; LFIRE-1
Entrez GeneID: 2267
Swissprot: Q08830
WB Predicted band size : 36.4kDa
Host/Isotype : Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human FGL1 (AA: 23-312) expressed in E. Coli.