This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.
Aliases: WVS; ENX1; EZH1; KMT6; WVS2; ENX-1; EZH2b; KMT6A
Entrez GeneID: 2146
Swissprot: Q15910
WB Predicted band size: 85.4kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human EZH2 (AA: 1-194) expressed in E. Coli.