The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases： EIF2B3;EIF-2B; EIF2Bgamma
Entrez GeneID ： 8891
Swissprot ： Q9NR50
WB Predicted band size： 50.2kDa
Host/Isotype： Mouse IgG1
Species Reactivity ： Human
Immunogen ： Purified recombinant fragment of human EI2BG expressed in E. Coli.
