The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Aliases： DLP1; DRP1; DVLP; EMPF; VPS1; DYMPLE; HDYNIV; DYNIV-11
Entrez GeneID： 10059
Swissprot： O00429
WB Predicted band size： 81.9kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human,Mouse,Rat
Immunogen ： Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
