This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
Aliases ： MRD62; PSD95; SAP90; SAP-90
Entrez GeneID： 1742
Swissprot： P78352
WB Predicted band size： 80.4kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human, Mouse, Rat
Immunogen： Purified recombinant fragment of human DLG4 (AA: 54-300) expressed in HEK293-6e cells supernatant.
