DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.
Aliases： p68; HLR1; G17P1; HUMP68
Entrez GeneID： 1655
Swissprot： P17844
WB Predicted band size ： 69.1kDa
Host/Isotype： Mouse IgG2a
Species Reactivity： Human,Mouse,Monkey
Immunogen： Purified recombinant fragment of human DDX5 (AA: 475-614) expressed in E. Coli.
