Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.
Aliases： P62; DYN4
Entrez GeneID ： 51164
Swissprot： Q9UJW0
WB Predicted band size ： 52.3kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human,Mouse
Immunogen： Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli.
