This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Aliases： IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; CHUK
Entrez GeneID： 1147
Swissprot： O15111
WB Predicted band size： 85kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human CHUK expressed in E. Coli.
