Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.
Aliases： ACHRE; CMS1D; CMS1E; CMS2A; CMS4A; CMS4B; CMS4C; FCCMS; SCCMS
Entrez GeneID： 1145
Swissprot： Q04844
WB Predicted band size： 54.7kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human,Rat
Immunogen： Purified recombinant fragment of human CHRNE (AA: extra 21-239) expressed in E. Coli.
