This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Aliases： CEA; CD66e
Entrez GeneID： 1048
Swissprot： P06731
WB Predicted band size ： 76.8kDa
Host/Isotype： Mouse IgG2a
Species Reactivity： Human
Immunogen： Purified recombinant fragment of human CEACAM5 (AA: 35-165) expressed in E. Coli.
