The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Aliases: T3G; IMD17; CD3-GAMMA
Entrez GeneID: 917
Swissprot : P09693
WB Predicted band size: 20.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD3G (AA: extra 23-116) expressed in E. Coli.
