The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Aliases: S1PR1; EDG1; S1P1; ECGF1; EDG-1; CHEDG1; D1S3362
Entrez GeneID : 1901
Swissprot : P21453
WB Predicted band size : 42.8kDa
Host/Isotype: Mouse IgG2a
Species Reactivity : Human
Immunogen : Purified recombinant fragment of human CD363 expressed in E. Coli.
