This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Aliases: TREM1; TREM-1
Entrez GeneID: 54210
Swissprot: Q9NP99
WB Predicted band size : 26.4kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human,Rat,Monkey
Immunogen : Purified recombinant fragment of human CD354 (AA: extra 21-205) expressed in E. Coli.
