This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.
Aliases: FZD4; Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; FZD4S
Entrez GeneID: 8322
Swissprot: Q9ULV1
WB Predicted band size : 60kDa
Host/Isotype : Mouse IgG1
Species Reactivity : Human
Immunogen: Purified recombinant fragment of human CD344 (AA: extra 37-222) expressed in E. Coli.
