The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Aliases : NCR3; 1C7; MALS; LY117; NKp30
Entrez GeneID: 259197
Swissprot: O14931
WB Predicted band size : 21.5kDa
Host/Isotype: Mouse IgG1
Species Reactivity : Human, Mouse, Rat
Immunogen : Purified recombinant fragment of human CD337 (AA: extra 19-135) expressed in HEK293-6e cells supernatant.
