This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
Aliases： JAM2; JAMB; JAM-B; VEJAM; PRO245; VE-JAM; C21orf43
Entrez GeneID： 58494
Swissprot： P57087
WB Predicted band size： 33.2kDa
Host/Isotype： Mouse IgG1
Species Reactivity ： Human
Immunogen： Purified recombinant fragment of human CD322 (AA: extra 29-238) expressed in E. Coli.
