Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Aliases： ICOSLG; B7H2; GL50; B7-H2; B7RP1; ICOSL; LICOS; B7RP-1; ICOS-L
Entrez GeneID： 23308
Swissprot： O75144
WB Predicted band size： 33.3kDa
Host/Isotype ： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human CD275 (AA: extra 19-256) expressed in E. Coli.
