This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.
Aliases ： PTA1; DNAM1; DNAM-1; TLiSA1
Entrez GeneID： 10666
Swissprot ： Q15762
WB Predicted band size： 38.6kDa
Host/Isotype： Mouse IgG1
Species Reactivity ： Human
Immunogen： Purified recombinant fragment of human CD226 (AA: extra 19-254) expressed in E. Coli.
