The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
Aliases: MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
Entrez GeneID: 4360
Swissprot : P22897
WB Predicted band size : 166 kDa
Host/Isotype: Mouse IgG1
Species Reactivity: Human,Mouse,Rat
Immunogen: Purified recombinant fragment of human CD206 (AA: extra(19-218)) expressed in E. Coli.
