This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.
Aliases : SIGLEC1; SN; SIGLEC-1; dJ1009E24.1
Entrez GeneID: 6614
Swissprot : Q9BZZ2
WB Predicted band size: 182.6kDa
Host/Isotype: Mouse IgG2a
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human CD169 (AA: extra 20-197) expressed in E. Coli.
