The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Aliases： THBD; TM; THRM; AHUS6; BDCA3; THPH12
Entrez GeneID： 7056
Swissprot ： P07204
WB Predicted band size： 60.3kDa
Host/Isotype： Mouse IgG1
Species Reactivity： Human
Immunogen ： Purified recombinant fragment of human CD141 (AA: extra 297-505) expressed in E. Coli.
